Mohammad Imran
Hossain

Marie Skłodowska-Curie Actions (MSCA) Doctoral Fellow · Karolinska Institutet

Connecting medical imaging, artificial intelligence, and cancer research.

I am a doctoral researcher in the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet , within the HER-CARE MSCA Doctoral Network, specializing in artificial intelligence and medical imaging for cancer research. My work integrates computational methods with imaging and biological data to advance risk assessment and precision medicine. My doctoral research focuses on developing and validating mammography-based AI models for short-term breast cancer risk prediction and evaluating the predictive value of a negative breast MRI. The aim is to inform evidence-based, personalized screening strategies that distinguish women who may benefit from supplemental imaging from those for whom longer screening intervals may be appropriate. More broadly, I am excited by research that brings together medical imaging, biological data, and trustworthy AI to better understand cancer and support personalized care.

Research interests

  • Medical AI
  • Breast cancer screening
  • Computational pathology
  • Trustworthy AI
  • Multimodal learning

Doctoral Research

AI-driven personalized breast cancer screening

How much reassurance does a negative scan provide?

A scan captures one moment; follow-up reveals what happens next. A negative result is reassuring, but it does not mean that every woman has the same future risk. Linking imaging information with subsequent cancer outcomes allows us to study how that risk changes over time. The research also examines how closely predicted risks match observed outcomes and whether models perform consistently across different populations. The figures below connect these questions with the workflow used to investigate them.

FIGURE 01 / THE STUDY QUESTIONSWho needs which screening, and when?
Women attending breast screeningDifferent risk profiles. A shared need for appropriate follow-up.

Three complementary questions

STUDY 01 / After a negative mammogram

Who remains at higher short-term risk?

Identify women who may benefit from supplemental imaging.

STUDY 02 / For women at lower predicted risk

Can screening intervals be extended appropriately?

Evaluate risk over five years and the potential for less frequent screening.

STUDY 03 / After a negative breast MRI

How does subsequent cancer risk evolve?

Assess whether MRI findings can help personalize future follow-up.

SHARED AIMEvidence for personalized screening

Match additional imaging and follow-up intervals to individual risk.

FIGURE 02 / THE END-TO-END APPROACHFrom patient information to future risk
01 / COMPLEMENTARY DATA INPUTS
Standard mammography views, panels A and B of the published figure
MammographyStandard mammography · panels A–B
Published example of contrast-enhanced and diffusion-weighted breast MRI
Breast MRISupplemental imaging subgroup
Clinical & epidemiological information

Age · BMI · family history · breast density · lifestyle / hormonal factors · polygenic risk, where available

02 / LEARN & COMBINE

Deep learning + multimodal risk modelling

Image-derived features + clinical covariates → time-to-event models

03 / VALIDATE AGAINST FOLLOW-UP

Estimate 1–5-year cancer risk

Linked cancer outcomes · discrimination & calibration · subtype and population analyses

01Higher-risk follow-up02Lower-risk intervals03Risk after negative MRI

LET’S CONNECT

Good research starts with a conversation.

Open to exchanging ideas and exploring collaborations in medical AI and cancer research.